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Re: Lykiri post# 675854

Sunday, 03/03/2024 12:02:36 PM

Sunday, March 03, 2024 12:02:36 PM

Post# of 700308
So what is Dr Mulholland talking about for a cure in 10 years? He talks about needing charity funds and BP drug donations. He talks about combinations of drugs used used in melanoma and blood cancers.

We know his recent IP-GLIO was charity funded with Yervoy contributed by Merck. But that failed badly, real badly. Yervoy+SOC was 22.7mOS vs SOC at 26.4mOS. Though 22.7 mOS for Yervoy+SOC does beat NWBO's ECA by 6 months (and the -L arm by 3 months).

Anyway, what is the combo he wants to push. Sounds like it will be Yervoy plus a CAR-T.

IMO, he is off the deep end if he thinks he can push through to results of a P3 (it will need a P1/2 first) in 10 years without BP cash. Though it may be he just means to the point of a P2 trial.
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