NorthWest Biotherapeutics Inc (NWBO)

[Chiugray]

Eagle8, Is it 12K/yr or 144K/yr? It is a good question to hone in on.

When we get to the capacity question. I can answer that as well. Currently in the facility we can manufacture up to 50 treatments per month in 2 cleanrooms. And this can be scaled up to quite a large number for glioblastoma for up to 1,000 patients per month. - Bosch June 2022 ASCO

The reason why I believe Bosch is referring to manual systems, and therefore Flaskworks 12X step up translates into 144K/yr:

- NWBO has a manufacturing (manual system) license and approval to import and manufacture GMP cell products under the Specials program from the MHRA (12/21/2021 PR). Public discussion of mfg capacity should by default be within that context. If it is talking about future and not yet approved Flaskworks, then public statements needs to clear and qualified. Bosch didn't, so I believe he was talking about manual systems.

- The "can be scaled up to" should be referring to theoretically adding cleanrooms, manual system, up to the 90K sq ft Sawston facility. I did an internal calculation exercise using a 1,100 sq ft (100 sq meter) cleanroom, 40 cleanrooms, 25 patients/mo, equals 1,000 capacity for facility. That would equal 44K sq ft or exactly 50% of the 88,345 sq ft facility.

- Plus I provided, in my previous post, my double check reference with the Autolomous video of their systems, which shows the 144K/yr is conservative and has potential for upside.