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Re: Steady_T post# 452657

Saturday, 02/24/2024 7:09:11 PM

Saturday, February 24, 2024 7:09:11 PM

Post# of 458251
In the adult Rett trial, the seizure risk decreased by 50%. That P3 trial was successful. In the pediatric Rett trial, we have anecdotal evidence of a Rett girl whose seizure frequency went from multiple daily to one every 3 weeks. It would be very hard to convince that family that the trial “failed” and that this medicine won’t be available to them. Seizure frequency is an endpoint that is much easier to “measure” than other endpoints, and to me is a strong indication of Anavex 2-73’s overall neurological efficacy. I hope the EMA and FDA see it this way.
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