NorthWest Biotherapeutics Inc (NWBO)

[exwannabe]

In reality NHS will reimburse up to 100K per QALY for rare and orphan diseases. I expect NICE will reimburse DCVax at 150K though I would be happy with 80-100K for UK market.

Yes. But the QALY for -L is not over a year.

The purported raw LY (life years gained vs SOC) can be seen from the KM chart. It is the difference in the areas under the curves through 5 years which can be eyballed as under .5 years. The Quality Adjustment reduces the value of a LY based on many factors. Most all P3 trials in oncology measure the Quality of Life as part of the trial. . NWBO failed to do this (because they repurposed and old P2 instead of designing a proper P3). Thus even if there is a real Q benefit it will not be established by the data.

The real question is why NWBO has not restarted the NICE process. NICE asked them a year ago for scientific evidence so they could start the evaluation. LP has not bothered to reply.

Could it be that LP knows the replies to their submission by experts in the community will be public?