Anavex Life Sciences Corp (AVXL)

[Steady_T]

Very interesting article. It sets the stage for 2-73 to be used as a prophylactic if it can get approval.

Interesting that the numbers are so low about those going on to get clinical symptoms of AD after this test diagnosis. 23%.

That leads to the question of how many needed to treat to prevent a case. We have seen with the statins that a very high number of people treated to prevent one death and that has been found acceptable.

The other thing that jumps out at me from this article is that the causes of AD are still not really known. This looks to me to still be searching for earlier symptoms and not finding causes. Given the low progression rate, assuming that continues to hold, it becomes clearer that Tau and plaques are late stage factors and not root causes. In a way this should help drive a nail into the coffin of Beta Amyloid plaque and Tau as targets for treatment and prevention.