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Re: sentiment_stocks post# 672892

Sunday, 02/18/2024 4:48:18 AM

Sunday, February 18, 2024 4:48:18 AM

Post# of 700003

Most chemo/rad psPD patients were screened from entering the main arm of the trial. Therefore, there were likely very few, if any, psPD from chemo/rad patients in either the treatment or control arms of the trial.


How is that?

The baseline MRI that screens out early progressions (and psPD) is 2 weeks after completion of RT+C.

Though numbers vary, papers generally say psPD presents weeks to months after RT+C. See https://radiopaedia.org/articles/tumour-pseudoprogression-brain-tumors

Also, the RANO criterion (not used to save time and money per LG) excludes images in the radiation zone for 12 weeks following RT+C as it is likely psPD.
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