NorthWest Biotherapeutics Inc (NWBO)

[exwannabe]

How can pseudo-progression affect rGBM? DCVax-L was administered to the 64 crossovers only after they had progressed. Please get your facts straight.

His facts are correct. The JAMA paper states clearly that because of psPD they could not differentiate psPD from PD. As such, the group of 66 had psPD patients in it. The psPD confoundment is not limited to immune treatment as some here falsely assert.

By the way, as a group, those 64 crossovers had a longer mOS than that of the 232 member Treatment group ...

No. It was 13.2 vs 19.3 months. I assume you are backing it time since surgery? That is mathematically flawed because you excluded early deaths from one group. Consider a trial where a single glass of grapefruit juice is served to GBM patients at year 5. The mOS will be something like 8 years. .