NorthWest Biotherapeutics Inc (NWBO)

[Lykiri]

At UCLA, Dr. Liau and other researchers are now testing whether the vaccine would be more effective in combination with a PD-1 checkpoint inhibitor. Checkpoint inhibitors are a type of immunotherapy that work by blocking proteins that stop the immune system from attacking cancer cells. While the vaccine allows T-cells to get inside of the tumor, the checkpoint inhibitors may allow T-cells to be more functional and better attack the tumor cells.

“Because of the heterogeneity of glioblastoma, I don’t think there is going to be one drug or one treatment that is going to be effective for all patients. The future of glioblastoma treatments is going to be these combination approaches,” Dr. Liau says.

Thanks for the reminder SkyLimit2022.

Comments from Prof.Steven Brem regarding the combo trial (01/26):

"What is very exciting and has a buzz in the Brain Tumor Community is a work that doctor Liau presented at the SNO meeting over a year ago in combination with checkpoint inhibitors".

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"When you use the checkpoint inhibitors you (indiscernible) to see that significant tail you are looking for. So that’s important to get out"

The 11th Neuro-Oncology #braintumor Symposium.
We have attendees From Around the World, 16 countries and 30 states.

It is still possible for you to register and receive our educational materials for up to one year. Click below to register.https://t.co/oouqj4yaza pic.twitter.com/IZWgbijIxK

— Steven Brem (@StevenBremMD) January 26, 2024