Anavex Life Sciences Corp (AVXL)

[tradeherpete]

Aren't most trials powered to see infinitesimal positive changes, hoping for any morsel of improvement to repeat enough to be Stat Sig?

The Blarcamesine Excellence trial blew it out of the water. Everyone got better, the only problem is, the Control Group got better too.

Gee, that's a real problem! Now what are we going to do???

Someone can't see the forest for the trees.

People might take some solace in that the bar for Rett and Alzheimer's couldn't be any lower.

The poor Rett patients suffer so many complications in their minute to minute life, adding these side effects from the FDA Approved Trofinetide would seem cruel.

Anxiety
decreased appetite
diarrhea
seizures
weight loss

And more commonly seen:

Fever
headache
muscle aches
sore throat
stuffy or runny nose
unusual tiredness or weakness

So, everyone improved in the Rett trial? And the fact that the Control Group did better as well is the problem?

I think the FDA will be offering Rett Patients a drug that makes them better without furthering their distress.

https://www.mayoclinic.org/drugs-supplements/trofinetide-oral-route/side-effects/drg-20545955