Anavex Life Sciences Corp (AVXL)

[williamssc]

When looking at other placebo-controlled Rett syndrome trials, ANAVEX®2-73 compares favorably in terms of absolute RSBQ improvements, with the caveat that cross trials comparisons have their limitations.

The key secondary endpoint, the Anxiety, Depression, and Mood Scale (ADAMS), trended favorably. In the same analysis, scores for all RSBQ and ADAMS subscales improved over the course of the study. Collectively, the RSBQ and ADAMS demonstrated improvements in multiple areas, impacting positively in particular repetitive movements, nighttime disruptive behaviors and social avoidance.

Nothing on seizures yet but we do know from the videos two children had pretty much stopped having seizure according to their parents. Really would like to know more on RWE. Canadian patients asked for compassionate use for a reason.