Annovis Bio Inc (ANVS)

[XenaLives]

My personal experience - flouroquinolones did it.

I was given FQ antibiotics for a fungal infection (idiotic, in retrospect) I had an adverse reaction, died, was resuscitated.

Then I was told that the resulting hypoxic brain damage was psychiatric and given more drugs that I couldn't tolerate.

Bottom line - it's a system that rewards Doctors for giving toxic treatments that is the problem.

Vaccines, COVID - not going to go there but the abuse is egregious.

FQ toxicity is probably a function of genetics.... but they don't test for it. So Ancestry.com will reflect a genetic pattern but it's actually a toxic drug that causes it.

"Research" like this makes me want to scream...

Multidrug resistance seen in bacteria today is one of the global threats as recognized by WHO. Misuse, overuse, and poor hygiene or infection control practices have all contributed to this rising problem [37]. Hence, repurposing clinically approved antibiotics for the treatment of other diseases would be economical and spare the redundancy of antibiotics. Some of the antibiotics, such as rifampicin, minocycline, benzylpenicillin, doxycycline, and bleomycin have shown anti-amyloidogenic activity, with rifampicin reaching clinical trials. This has prompted us to study another antibiotic for its anti-amyloidogenic behavior [[38], [39], [40], [41], [42], [43], [44]].

Levofloxacin is a fluoroquinolone (Fig. 1) with bactericidal activity against Gram-positive and Gram-negative bacteria including Mycobacterium tuberculosis. Emergence of levofloxacin-resistant strains of bacterium have been reported [[45], [46], [47]]. Levofloxacin has a favorable cerebrospinal fluid penetration and expected blood brain barrier penetrability [48].

Because of these properties, we investigated the possibility that levofloxacin could be effective in interfering with the amyloid formation by human lysozyme. We first investigated the possible mechanism of action of levofloxacin in this regard by detailed biophysical in vitro studies and computational analyses involving molecular dynamic simulations and docking, and further extended those studies by testing the effects of levofloxacin on the cytotoxicity of lysozyme aggregates using human red blood cells.

https://www.sciencedirect.com/science/article/abs/pii/S000398612100326X