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Saturday, 12/30/2023 3:48:04 PM

Saturday, December 30, 2023 3:48:04 PM

Post# of 688475
I know I've seen a bar chart that shows many patients with different solid cancers with the longest survivor on the top, still alive with pancreatic cancer. If we can find that chart I suspect we'll find 15 different cancers documented on it. Each patient in the chart is designated as living or decease at the time the chart was created.

I have no idea if this, and further documentation about each patient, was included in the UK filing in hopes they'll go with a tumor agnostic label, or if only information on brain cancers were included. I say brain cancer, not GBM, because GBM was redefined during the trial so some of the patients in the database would no longer be considered GBM patients, but all are certainly brain cancer patients. I'm sure that other forms of brain cancer were not in the trial, but hopefully with GBM being the most serious of brain cancers, the label will be at least for all brain cancer patients.

If they don't get a tumor agnostic label the question may be, do they do one trial that enrolls patients with a variety of cancers, or do they run several smaller trials, each for one specific cancer. The same question would also apply to a future DCVax-Direct trial.

I still hope that when NWBO announces acceptance from the UK they also announce when the next Annual Meeting will be held. With the exception of things like the Big Biz Show, we've really received very little guidance in a year, it's time that we should be told what progress has been made, and some forecast for where we're going.

Happy New Year's,

Gary
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