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Re: growingpain post# 443392

Wednesday, 12/20/2023 5:41:55 PM

Wednesday, December 20, 2023 5:41:55 PM

Post# of 462003
Your argument has merit. The genes that had higher levels of expression were not prespecified so in terms of a conclusive demonstration of effect the data is not more than suggestive. That is basic stats.

The Excellence trial is also collecting substantial genetic data. If those same patterns of changes show up in the Excellence trial then the data becomes very strong because at that point the data points are no longer random relationships but appear to be causal.

Also the heat map shows patterns or clusters of genetic changes related to energy production and metabolism. That clustering is suggestive of an effect rather than a random occurrence.

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