Thank You, No problem. Warren Buffett never bought Qualcomm, Nvidia, Vertex, Seagen or Alnylam when they were small companies.
I think it takes more skill to identify the small hidden gem than it does to buy the large and established and just hold them.
Qcom is a perfect example, the whole world was using TDMA (time division multiple access) and GSM (global standard for mobile communication) ... and Qualcomm had a little known military technology called CDMA (code division multiple access). Once I investigated and understood the difference, it was a no brainer that CDMA and Qualcomm would take over the world.
It's a bit easier to say "I think I'll buy Geico and just hold it". I also read Benjamin Graham and Peter Lynch when I was young.
I get the whole P/E and P/E/G ratio thing. It's just more fun hitting home runs than singles.
When you keep hitting home runs long enough, you get to be down as much as I am in MRKR and not have it effect your life and as I said, if MRKR lives up to it's potential with AML or Lymphoma or Pancreatic, it's got an up 10,000%+ in front of it.