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Wednesday, 10/11/2023 4:33:20 PM

Wednesday, October 11, 2023 4:33:20 PM

Post# of 461428
Could this happen to Anavex?

Earlier today someone posted on the day’s explosion of the TPST (Tempest Therapeutics, Inc) share price. I clicked around to see what was up (beyond the share price).

Tempest, like Anavex, appears to be a small biotech start-up presently with no product revenues. The company, founded in 2017, focuses on innovative (proprietary) cancer treatments by “...developing first-in-class small molecule therapeutics to treat cancer through mechanisms that directly kill tumor cells and activate tumor-specific immunity.” Another small start-up biotech with no products to sell; just some “innovative” disease treatment concepts, centered on cancer and the immune system.

https://ir.tempesttx.com/

In a news release this morning the company announced that data analysis of a “Phase 1b/2 clinical study in which TPST-1120, Tempest’s PPAR antagonist, shows clinical superiority in multiple study endpoints when combined with atezolizumab and bevacizumab in a randomized comparison to atezolizumab and bevacizumab in the first-line treatment of patients with unresectable or metastatic hepatocellular carcinoma (“HCC”).

In combination with other drugs, the Tempest drug was shown to work for this particular cancer.

https://ir.tempesttx.com/news-releases/news-release-details/tempest-releases-new-data-demonstrating-superiority-tpst-1120

Obviously, the “market” liked what it learned (as though markets are personalities). At the close yesterday (10 Oct) the TPST share price was what it has been for some time, in the narrow range of $0.23. Then, this morning the news release was read and the share price ascent went up at a steep angle all day. At a good number of times during the day, the stock got a trading halt; apparently to cool things down.

At 4pm Eastern, the share price closed today at about $10.00; was varying drastically. Who knows where (or if) the share price will settle when after-hours trading finally settles on a price?

The day before, the closing TPST share price was $0.23. In 24 hours the share price increased and closed at, shall we say, $10.00. $10.00/$0.23 = 43.47826. In 24 hours, the TPST share price increased in value over 43 times; a percentage increase of 4347.83%.

If Anavex were ever to have a similar press release, announcing similar results for blarcamesine against Rett and/or Alzheimer’s, and the “market” responded accordingly, with an Anavex start price at a mere $5.00, the next day’s closing share price would be $217.39.

With even a fraction of such an Anavex share price increase, it would seem that a lot of wives of husbands betting big on Anavex failure, holding uncovered AVXL short positions, would like to learn just why this explosive price increase could never happen with Anavex. Please, tell us why the shorties and their wives are not at risk with such a scenario.
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