Ardelyx Inc (ARDX)

[Whalatane]

PDFA date is Oct 17th . Will IMHO be approved at least as a combo with the existing binders .
Existing binders cause constipation in many dialysis patients https://www.kireports.org/article/S2468-0249(19)31529-3/pdf so those that have this issue are probably the first to try Tenanapor as the most common AE is a looser stool with diarrhea a problem for some.
I expect them to start on a low dose and titrate as necessary .
If they can eventually get 20% of these patients onto Tenanapor thats about 100,000 patients in the US alone
Kiwi