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falconer66a

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falconer66a

Re: Joseph_K post# 433397

Friday, 09/29/2023 4:49:40 PM

Friday, September 29, 2023 4:49:40 PM

Post# of 461432
A mouse model with GBS.

Falconer, are there genetically modified mice that display GBS symptoms for Anavex to experiment on?


Yes,

L31/CD4-/- mice mimic most parts of clinical and pathological signatures of GBS in human; thus providing an unconventional opportunity to experimentally explore the critical events that lead to spontaneous, autoimmune demyelinating disease of the peripheral nervous system.


https://actaneurocomms.biomedcentral.com/articles/10.1186/2051-5960-2-5
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