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Re: ExtremelyBullishZig post# 432598

Monday, 09/25/2023 8:31:00 AM

Monday, September 25, 2023 8:31:00 AM

Post# of 473590
Actually, Ziggy, in the P2a trial, there were six participants, a/k/a "Strong Responders," whose MMSE score increased thru Week 57, and five of those thru Week 109. These were the only ones who improved in that trial and each was DPZ-naive.

MMSE Scores by Week
SR 0 31 57 Inc (Dec) 109 Inc (Dec)
1009 20 24 26 6 29 9
1011 20 23 22 2 21 1
1014 20 22 25 5 25 5
2006 25 28 29 4 28 3
2010 25 28 28 3 28 3
1013* 22 24 24 2 18 -4

22 17
Average 3.7 2.8
Average w/o 1013 4.0 4.2

* Significant decline from Week 57 (24) to Week 70 (18)


As to the P2b/3 trial, only Anavex knows if there were any Strong Responders and, if so, how many, though indications from data presented are that there are some.

P.S. Sorry, Ziggy, as the chart does not line-up properly, so you'll have to use your imagination in structuring the columns.
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