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Re: hoffmann6383 post# 630026

Tuesday, 09/12/2023 4:22:11 AM

Tuesday, September 12, 2023 4:22:11 AM

Post# of 716347
Hoffy, with the absolutely startling enhancement of DCVax-L's efficacy that has been shown when pembrolizumb and poly-ICLC are added to the regimen, I can see that a trial of the combo should be mounted if only to set a benchmark for the efficacy of the combination against which all future trials of different drugs or combinations can be adjudged.
However, such a further study should not delay DCVax-L's contribution both to saving lives and to replensihing NWBO's coffers because once it is licenced every neuro-oncologist who has kept up to date with what is going on in the DCVax-L firmament is going to routinely prescribe the triple combination unless such a "benchmark" study were to show (unbelievably on current findings) that the addition of one or both extra components added nothing to DCVax-L's efficacy.
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