Anavex Life Sciences Corp (AVXL)

[powerwalker]

Tred, this is what I found:

In AD dementia, the mean prevalence of amyloid positivity was 88% (95% CI, 85% to 90%, Figure 2A). The prevalence decreased with age from 93% (95% CI, 90% to 95%) at age 50 to 79% (95% CI, 73% to 85%) at age 90 (ß for change in GEE estimated prevalence of amyloid positivity per year, -0.032 [95% CI, -.050 to -.014], P < .001).

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517678/#:~:text=In%20AD%20dementia%2C%20the%20mean,050%20to%20%E2%88%92.

As to those over 60 who experience amyloid issues, I found this:

Individuals with elevated amyloid represented 20.4% of the older adult sample (≥60 years).

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280058/

Tred, not sure if the blood test will have a correlation bias between 1) amyloid and 2) AD [if 1) = Y, then 2) is Y] or if the intent is to determine other biomarkers than amyloid that will predict Alzheimer's. I'll let the Board know what the results are in 4-6 weeks.