Monday, August 21, 2023 7:19:35 AM
Thanks for reply, but I think you’re mixed up. Every cancer trial attempts to measure and predict survival.
PFS is a surrogate predictor of OS. The PFS data will be available sooner. The trial will also collect OS data of course, but OS data are not available as early as PFS data are.
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This statement is illogical. PFS does predict OS—that’s its purpose. Cancer trials collect data on both, but one data set is available much sooner than the other. Once OS is finally reached, OS either confirms or invalidates the earlier PFS data. PFS is not a hard endpoint—PFS predicts the hard endpoint of OS.
Believe carefully. This is the greatest and most powerful lesson that I have learned since arriving on Earth. Examine what you believe about yourself most importantly, and then believe carefully as you interact with the world.
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