Amarin Corp Plc (AMRN)

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More evidence that “it’s the EPA, stupid”!

New 12 week study from Australia

“Improved arterial inflammation with high dose omega-3 fatty acids in patients with elevated lipoprotein(a): Selective effect of eicosapentaenoic acid?”

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https://www.lipidjournal.com/article/S1933-2874(23)00249-0/fulltext

Highlights

•Patients with elevated Lp(a) are at an increased risk of atherosclerotic cardiovascular disease partly due to pro-inflammatory effects of elevated Lp(a).

•High dose ?-3FAs lowered arterial inflammation, as measured by SUVmax using 18F-FDG PET/CT, in patients with elevated Lp(a).

•Reduction in arterial inflammation was inversely associated with on-treatment plasma levels of EPA, but not DHA or triglycerides, suggesting a favourable direct effect of EPA.