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Re: sentiment_stocks post# 619697

Friday, 08/11/2023 7:30:16 PM

Friday, August 11, 2023 7:30:16 PM

Post# of 689198

So this article entitled "Dendritic cell vaccination for glioblastoma multiforme patients: has a new milestone been reached?" from 7-28-23 is a decently positive one.
https://cdn.amegroups.cn/journals/pbpc/files/journals/3/articles/77315/public/77315-PB1-6789-R1.pdf

Journal: Translational Cancer Research
Authors: Stefaan W. Van Gool^, Jennifer Makalowski, Linde F. C. Kampers, Peter Van de Vliet, Tobias Sprenger, Volker Schirrmacher, Wilfried Stücker



Thanks for sharing sentiment.

Individualized multimodal immunotherapy anno 2023 as part of a multiphase combined treatment strategy for cancer: piloting of an innovative treatment concept in the domain of Glioblastoma Multiforme.
Stefaan W. Van Gool, Peter Van de Vliet, Linde F. C. Kampers, Jennifer Makalowski, Tobias Sprenger,
Volker Schirrmacher, Wilfried Stücker

At 10/03/2023, the IOZK team received the invitation, on behalf of the editorial office of Translational Cancer Research, to write “in light of your excellent academic background” an Editorial Commentary on the “attached article entitled “Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.” (written by Liau L.M, Ashkan K, Brem S, et al) published on JAMA Oncol in 2023.



Can the scientific community consider this publication (11) as a new milestone in the development of DC vaccination as active specific immunotherapy, aimed to improve the OS of patients with GBM? The answer is definitively yes. It is the first phase III controlled report that shows an improvement of the OS in patients with GBM. For the first time, a level I of clinical research evidence in evidence-based medicine is reached (191), and extends the Level IIa clinical research evidence already observed with systematic reviews of phase I or II clinical trials (129, 130, 131, 132, 133, 134).


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