NorthWest Biotherapeutics Inc (NWBO)

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This Al Musella?

Straight from virtualtrials.org. "I would use Optune."

Q: You direct an established foundation that supports research and information about brain tumors. What would you do if you yourself were diagnosed with a glioblastoma multiforme (GBM)? A: Now that GBMs are in the news again, I would like to discuss what I would do if it happened to me — an adult in otherwise good shape. There are several choices. Standard of care: Surgery, radiation, Temozolomide. Chance of 5 year survival is about 5%.

Standard of care PLUS Optune. Bumps my chance of 5 year survival up to 13% with no added toxicity. Recent data shows we can move up to 29% 5 year survival if the optune device is used at least 90% of the time!
Optune. We are put into a very tricky situation here. Many trials will disqualify you if you use Optune, but Optune has the highest survival rates in large trials. So you are being asked to gamble a known doubling of chances of 5 year survival for an unknown experimental treatment that might or might not help, and you might even be assigned to a control group. I would use Optune.