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Saturday, July 22, 2023 1:37:18 PM
https://www.rnz.co.nz/national/programmes/saturday/audio/2018899512/prof-danny-altmann-the-burden-of-long-covid
More work is desperately needed on the wider topic of viral persistence in medicine, he says. In the case of long Covid, this is the idea that 'reservoirs' of the coronavirus might remain in the body after the acute phase of the disease, and cause ongoing disease.
The theory is Altmann's favourite as it potentially offers low-hanging fruit: "Because if you think about it, in terms of potential treatments ...if we were really good at identifying the people who have got a problem because they can't clear the virus and have a persistent reservoir, surely we could just come in with the appropriate antivirals or the appropriate monoclonal antibodies and make them better."
And then the crux --However, the challenge there lies in identifying the people who might have a viral reservoir affecting them.
The gold standard to test for viruses lurking in the body is with a gut biopsy, but "it wouldn't be ethical to go around taking out bits of people's guts to have a look," Altmann says. So new ways to test this would need to be worked out.
EXACTLY what has been talked here--linked here for >>1 year
At least some/most of researchers are realizing this IS the issue. Viral persistence.
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