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Re: hankmanhub post# 609394

Thursday, 07/13/2023 2:36:51 PM

Thursday, July 13, 2023 2:36:51 PM

Post# of 704240
This quote talks of 40 patients in the Direct trial:
Northwest Biotherapeutics Announces Data To Date From DCVax-Direct Phase I Trial
Published: Jun 01, 2015

BETHESDA, Md., June 1, 2015 /PRNewswire/ -- Northwest Biotherapeutics (NASDAQ: NWBO) ("NW Bio"), a U.S. biotechnology company developing DCVax® personalized immune therapies for solid tumor cancers, over the weekend in Chicago released promising new data on their Phase I trial of DCVax-Direct for direct injection into all types of inoperable solid tumors.

The patients enrolled in the trial had late stage cancers, with an average of three inoperable tumors. The patients had failed multiple prior therapies and had a poor prognosis.

The trial enrolled 40 patients, and 39 were evaluable. A conservative treatment regimen was used. Although the patients had multiple inoperable tumors, only 1 tumor was injected with DCVax-Direct. The treatments included only 3 injections in the first 2 weeks (Day 0, 7 and 14), and up to 3 additional injections spaced months apart thereafter (Weeks 8, 16 and 32), over a total period of 8 months.
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