NorthWest Biotherapeutics Inc (NWBO)

[Lykiri]

The final product is tested for identity, purity, potency, and stability against pre-established release criteria for the product. And then as I just said, there are a number of additional tests (sterility, endotoxin, mycoplasma) to ensure that the product contains no contaminants. All of this testing takes about a month or more.

Hyperopia,
Thanks for the clarification. I didn’t know that. You are correct (and I was wrong) that they are using fresh, not frozen leukapheresis material.
Yesterday I asked LL if it's possible to manufacture an autologous dendritic cell vaccine (DCVax-L) by using cryopreserved apheresis material.
Here is LL’s reply:

June 29, 2023

Hi xxxxx,

It is potentially possible, but the viability and potency of the dendritic cells may not be as good as when they are fresh.

LL