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Re: ORBAPU post# 410618

Tuesday, 06/13/2023 6:13:20 PM

Tuesday, June 13, 2023 6:13:20 PM

Post# of 425795
ORBAPU... on whether the BRAVE study is blinded...

An important part of the study is cognitive performance...
The study specifies" Time Frame: 18 months cognitive performance"

IMO the examiners for this part of the study would be difficult to be blinded...unless the cognitive evaluation were done by a series of questions to be given to patients for their written multiple choice answers...This would not be a very good study of patients' cognitive performance over the time period and I doubt this would be the chosen method for evaluation of cognitive performance.

The lab parts of the study could, however be blinded.
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