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Re: Doc328 post# 417842

Tuesday, 06/06/2023 11:09:16 AM

Tuesday, June 06, 2023 11:09:16 AM

Post# of 464890
Anavex provided answers and reduced the Uncertainty spun by the FUD narrative. Trofinetide was approved on the same endpoints Anavex will also be using, thus, for the final analysis, there is more clarity now than the uncertainty your comment is elicits.

Though it does call into question whether the Avatar endpoints are adequate for Anavex to claim its a phase 3 rather than a 2b.


coprimary RSBQ and CGI-I change in means vs. RSBQ-AUC



IMO the combined data package of adult and pediatric study analysis will lead to a Rett Syndrome approval regardless of if the adult trial is considered a P3 or not.
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