Wednesday, May 17, 2023 7:03:24 PM
On November 08, 2022, the Company licensed from Therapeutic Solutions International, Inc., the following patent:
·Application No.: 63/161526 titled as: Pluripotent Stem Cell Derived Dendritic Cells and Engineered Dendritic Cells for Cancer Immunotherapy.
Abstract:
Disclosed are populations of dendritic cells generated from stem cells capable of inducing immunity towards cancer. In one embodiment said dendritic cells are generated from allogeneic inducible pluripotent stem cells, for some uses, said pluripotent stem cells are genetically engineered/edited to induce cancer specific immunity and/or resist immunosuppressive effect of tumor derived microenvironment. In one embodiment pluripotent stem cells are transfected with cancer stem cell antigens such as BORIS and/or NR2F6.
On February 15, 2023, the Company licensed from Therapeutic Solutions International, Inc., the following patent:
Application No.: 63/445872 titled as: Enhancement of Anti-Angiogenic Cancer Immunotherapy by Abortogenic Agents .
Abstract:
The current invention provides means of suppressing tumor associated immune inhibition through administration of progesterone and/or glucocorticoid receptor antagonists such as RU-486. In one embodiment the invention provides the concurrent utilization RI-486 and anti-angiogenic immunotherapy. In another embodiment, abortogenic inhibitors of immunity such as indolamine 2,3 dioxygenase are administered together with RU-486 and/or anti-angiogenic immunotherapy. Various antiangiogenic agents can be utilized in the practice of the invention including the ValloVax immunotherapy and/or the StemVacs-V therapy.
You also bought from us the IND for Breast Cancer using the first listed patent. When you started your company you owned 100% of the stock but you need to raise $4,000,000 for clinical trial.
What will your stock structure look like to support all this, fund the trial for phase 1 and keep control. You need to hire chief science officer, chief medical officer, chief financial officer and they take equity in lieu of cash salary.
Tell me what you would do to get all this going and still have lots of ownership?
Cable
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