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Re: exwannabe post# 592456

Thursday, 05/11/2023 8:02:21 PM

Thursday, May 11, 2023 8:02:21 PM

Post# of 700308
Yes of course London was using the exact manual process that was used during the trial - it was the the legacy process established by Cognate that was used to manufacture for compassionate use in the UK. That manual process was then transferred to Sawston for the initial investigational license there.

I can’r recall if London has a commercial license. If it’s only an investigational license, then Advent could manufacture for the pediatric trial or another small trial there. That’s the only reason I can think of to keep the facility open using an obsolete, less efficient, manual process. I think it’s likely the new established semi-automated process will be transferred to London and used to apply for a commercial license if it doesn’t already have one, and then the facility could be used for extra commercial capacity, or for small clinical trials.
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