Anavex Life Sciences Corp (AVXL)

[bas2020]

You're completely wrong...

Anavex provided two means scores: ADAS-Cog and CDR-SB. Each met their endpoint.
Company stated that all endpoints were met, which includes ADCS-ADL mean score (though not provided)

Anavex presented Odds Ratios because of the astonishingly positive results of the group of treated patients who were Super Responders. These exciting results have never been produced or presented by any company before; therefore, Anavex highlighted those results.

Regarding the Odds Ratios, here's how you get to >3x and >4x for the relative n's, using ITTs of 320 and 160 (these #s don't have to be exact for this exercise):

1.84 = n2(160 - n1) / n1(320-n2). Solving for n2...

n2 = (588.8 * n1) / (160 + .84 * n1)

Plug in any number for n1 and you'll get an n2 that is >3x of n1.

Do the same exercise for ADCS-ADL OR and you'll get n2's that are >4x of n1's.

I hope you've learned something from this exercise and we can discontinue this discussion.