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Re: powerwalker post# 413190

Monday, 05/01/2023 9:23:50 AM

Monday, May 01, 2023 9:23:50 AM

Post# of 465334

Is it possible that hypertension measurements were a data point Anavex collected in the P2b/3 but did not disclose it?



We know a lot of data has not yet been disclosed. Most notably the ADCS-ADL means.

Vital signs have been taken at every physical visit for all studies I've ever been part of --- therefore, Anavex should have this data on 500-600 adults for various time points. However, many of these patients would have started with normal BP so the hypertension at entry n would be low - hence the AD trial can give a hint of efficacy but would be insufficient to prove it. A separate hypertension study would need to be performed. On the positive side these are usually far shorter and less expensive per person than a CNS trial
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