WiMi Hologram Cloud Inc (WIMI)

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WIMI launches real-time network holographic microscope interaction technology, which can be widely used in education and scientific research.

Source
https://t.cj.sina.com.cn/articles/view/1765776051/693f9ab30200113mp?from=tech

April 12, 2023

It is reported that WIMI (NASDAQ: WIMI) has launched a real-time network holographic microscope technology, which can significantly improve the resolution along the optical axis (horizontal and axial resolutions: 0.4µµm and 0.8µµm respectively). LEDs, each with a different color (RGB), hit the sample from three different directions. Each channel of the camera records an independent hologram created by the interference between incoming light and light scattered by an object. These three holographic digital images are transferred to a GPU algorithm to compute three corresponding volumetric reconstructions. Each of the signals currently in the reconstruction suffers from poor axial resolution, but their overlapping returns a volumetric image whose isosurface profile closely approximates the surface of simple microscopic objects.

According to the data, WIMI WIMI holographic real-time network holographic microscope technology supports user interaction through virtual reality devices, and can use gestures (that is, "grab") or more complex remote control interaction methods to achieve independent creation, destruction, selection and movement. When the engine detects an event related to the creation, destruction, or displacement of a snap, data describing the updated snap configuration is sent to the "holographic engine" over a network connection. The holographic engine runs on a computer that controls the optical hardware in a separate lab.

When an update request is received from the "VR Engine", the Holographic Engine computes an optimized digital hologram on the GPU and displays it directly on the SLM. A collimated infrared laser beam is reflected from the SLM and acquires a phase modulation such that the resulting diffraction-limited spot has the same spatial arrangement as its virtual counterpart after propagating through the microscope objective. Each of these spots acts as an optical trap, which can be used to grasp and manipulate small dielectric objects. Typically, capture rearrangements will result in rapid motion of nearby objects, captured in a holographic image and processed in real-time by a "holographic engine". The obtained volumetric reconstructions are segmented to extract relevant geometric features of all identified objects. This geometric data is sent back to a "VR engine" to update the object's geometric parameters, providing a virtual representation of the real object interactively manipulated under the microscope, as shown here.

The SLM will be refreshed at a rate of 60 Hz, and the minimum delay time corresponding to the holographic image display is 17 milliseconds, which can ensure a smooth interactive operation experience. Simultaneously displayed phase modulation on the SLM to generate an optical capture at the position indicated by the 3D arrangement of the virtual handle, showing the original hologram recorded on the three color channels of the camera before being numerically reconstructed, tracked and rendered on the VR headset picture. Using a virtual hand to grasp objects and arrange them into 3D holographic configurations that can be inspected immersively and in real time, and allow direct manipulation through gestures and real-time immersive feedback. Microassembly tasks can be greatly simplified, especially for users with no previous microscope and capture experience.

WIMI (NASDAQ: WIMI) real-time network holographic microscope interaction technology. A series of tools are also implemented to track objects and observe the temporal evolution of their coordinates on a display. Using holographic optical tweezers capable of dynamically aligning multiple snaps in 3D, we can precisely arrange multiple colloidal particles or living cells in controlled spatial configurations to study their random behavior under reproducible initial conditions, or their Biological interactions during growth, grasping and rotation of microfabricated objects with complex shapes can also be used as tools for advanced microscopy applications. In this regard, virtual reality interfaces can simplify and accelerate the assembly of multicomponent microsystems and allow direct manipulation through gestures and real-time immersive feedback.

Holographically imaging objects as large as the wavelength of light, like bacteria, is quite a challenging task. Volumetric reconstruction represents the convolution of the actual object shape by a point spread function, which approximates a 3D Gaussian and leads to blurring of the final 3D image (especially along the vertical axis). WIMI WIMI holographic real-time network holographic microscopy technology has a reliable prior information about the shape, and infers the geometric parameters of these shapes through volume reconstruction, using the volume image reconstructed by the marching cube algorithm, which is executed on the "holographic engine" GPU, The output polygonal mesh, whose vertices and triangles are sent over the internet to a "VR engine" for real-time rendering.

WIMI's (NASDAQ: WIMI) real-time network holographic microscope interaction technology presents a powerful interface through virtual reality to merge 3D microscopy and holographic technology for micromanipulation. Provides an immersive interactive experience of microscopic phenomena. We can enter laboratories on a chip, walk on microscope slides, observe dynamic phenomena happening around us in real time, and use virtual hands to grasp, move and construct 3D spatial arrangements of microscopic objects and living cells. This approach can be extended in many different directions. All of this holographically interactive digital information can be used to explain to students, and to conduct experiments and observe the microscopic world in the first person, providing a unique and powerful experience of the physical laws governing the microscopic world populated by cells and colloidal particles.