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Re: willyw post# 2495

Wednesday, 04/26/2023 12:16:44 AM

Wednesday, April 26, 2023 12:16:44 AM

Post# of 3013

For me the up front money secured by Mavyret agreement means that there is no money bottleneck. It puts ENTA in a stronger bargaining position if there were to be a partner. You don't want to be in a position where you are desperate to deal. (that's my opinion)



Exactly. The reason why ENTA didn't get a better royalty deal from ABBV with their HepC drugs is they were in a position of weakness. This financial deal means ENTA is now in a position of strength and they don't desperately need a deal. Obviously it all depends on the data from the EDP-235 phase 2 trial, where likely the safety data is the biggest potential worry. ENTA could theoretically fund their own phase 3 trial alone but I am sure they would rather partner rather than take the full risk themselves. I can see from you posts your were response to Jake, but that guy claimed the FDA would never allow anyone to run a phase 3 trial, which is nonsense. However, it is telling he now he now says ENTA will do it alone so I guess he "thinks" the FDA changed its mind. Of course the financial deal ENTA made give them freedom and some leeway.

The world needs better anti-Covid drugs than Paxlovid as Covid will be around a long time. Obviously, the resident board "expert" Jake does not agree as foolishly stated that Advil would show non-inferiority to Paxlovid. I must admit I added a bit more today at $34.75. The NASDAQ was down 2% as McCarthy threatens to crash the economy.
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