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Important to mention that no Pain Remedy 'works for everyone'

When It Comes To Pain Relief, One Size Doesn't Fit All
September 26, 2011 NPR

"In a massive review of current studies and research published earlier this month, scientists at Oxford University in England examined 350 different studies involving about 45,000 patients. They looked at doses of single painkillers as well as combinations of drugs, totaling 38 different pain medications — everything from acetaminophen, aspirin and ibuprofen to more powerful opiate derivatives."

"Biochemist Andrew Moore headed the study, which aimed to explore whether one medication worked "best" for most people. Their conclusion: No. Certain pain medications which worked to relieve pain for certain individuals were barely noticeable for others."

https://www.npr.org/sections/health-shots/2011/09/26/140705557/when-it-comes-to-pain-relief-one-size-doesnt-fit-all

'Number Needed to Treat', NNT, is a standard used to evaluate the effectiveness of Pain Relievers. It measures how many patients must be treated for one to achieve a 50% reduction in their pain. The closer to a value of 1 the better the medication.


Common Pain Meds and NNT score:

Medication ............ Type of Medication ..................... Study Size ....... NNT
Diclofenac ..............100 mg Prescription NSAID ..................545 ..............1.8
Celecoxib................400 mg Prescription NSAID ................ 298 .............. 2.1
Ibuprofen ............... 400 mg Prescription NSAID .............. 5456 ..............2.5
Naproxen ............... 400 mg Prescription NSAID ................ 197 ...............2.7
Ibuprofen ............... 200 mg OTC NSAID ......................... 3248 .............. 2.7
Oxycodone 10 mg +
Acetaminophen ......1000 mg Prescription opioid ................. 83 ............... 2.7
Morphine ....................10 mg Injectable opioid ................... 948 ............... 2.9
Oxycodone 5 mg +
Acetaminophen ........ 325 mg Prescription opioid ............... 149 ............... 5.5
Tramadol ....................50 mg Prescription opioid ................ 770 ...............8.3

https://www.nsc.org/getmedia/8ecdc0e5-ae58-43e8-b98b-46c205e1c2b2/evidence-efficacy-pain-medications.pdf