NorthWest Biotherapeutics Inc (NWBO): Concerning DCVax-Direct: Exwannabe state...

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Re: exwannabe post# 583102

Wednesday, 04/05/2023 12:49:13 PM

Wednesday, April 05, 2023 12:49:13 PM

Concerning DCVax-Direct: Exwannabe states

NCT01882946 is the Direct P1/2 that vanished after the P1 phase has no responses in any patient.

But these Physicians and Doctorates conclude the following (see below).

Vivek Subbiah; Ravi Murthy; David S. Hong; Robert M. Prins; Chitra Hosing; Kyle Hendricks; Deepthi Kolli; Lori Noffsinger; Robert Brown; Mary McGuire; Siquing Fu; Sarina Piha-Paul; Aung Naing; Anthony P. Conley; Robert S. Benjamin; Indreshpal Kaur; Marnix L. Bosch

Conclusions: Intratumoral aDC injections were feasible and safe. Increased production of specific cytokines was correlated with SD (stable disease) and prolonged survival, demonstrating a link between the functional profile of aDCs prior to injection and patient outcomes. Clin Cancer

https://aacrjournals.org/clincancerres/article/24/16/3845/277824/Cytokines-Produced-by-Dendritic-Cells-Administered

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