Anavex Life Sciences Corp (AVXL)

[falconer66a]

Ok, Here's the Data from the Indian study.

falconer, could you please share what kind of oil was used? Thank you!

Black Seed Oil, from the black seed or black cumin plant seeds. Nigella sativa is the Latin name of the plant. It's commonly grown and consumed in the Middle East.

The active ingredient in the oil, which is pressed out of the seeds of the black seed plant, is thymoquinone. Do a PubMed search on thymoquinone. Dozens of studies on it. Renders all sorts of health benefits.

If thymoquinone were a synthesized drug chemical it would be worth billions to the drug company that would hold its patent. But it's a natural component of a commercial plant so it can't be patented.

Here's the abstract of the study in India, for older men suffering from kidney failure (stage 4 chronic kidney disease):

Asian Journal of Pharmaceutical and Clinical Research; Vol 9, Issue 2, 2016
EVALUATION OF EFFICACY AND SAFETY OF NIGELLA SATIVA OIL SUPPLEMENTATION IN
PATIENTS OF CHRONIC KIDNEY DISEASE

ABSTRACT
Objective: To evaluate efficacy and safety of add-on therapy of Nigella sativa oil in patients of stage 3 and 4 of chronic kidney disease (CKD).
Materials and Methods: The study was conducted in a tertiary care center of north India in stage 3 and 4 patients of CKD. It was a prospective, comparative, and open label study. Patients were randomly divided into two interventional groups. Group I (Control) received conservative management of CKD while Group II (Test) received conservative management along with N. sativa oil (2.5 mL, per orally, once daily) for 12 weeks.
Hemogram and renal function tests were done, and adverse events were recorded at 0, 6, and 12 weeks of treatment.
Results: After 12 weeks of treatment, there was a progressive improvement in clinical features and biochemical parameters in both the groups, but it was more marked in the test group compared to control group. Both groups showed gradual improvement in the biochemical parameters as compared to their pre-treated values which were more marked in N. sativa oil supplemented group. There was a reduction in blood glucose, blood urea, serum creatinine, and 24-hr total urine protein. There was an increase in hemoglobin, 24-hr total urine volume, and glomerular filtration rate.
Conclusion: N. sativa oil supplementation along with conservative management is efficacious and safe in averting the progression of disease in stage 3 and 4 patients of CKD.