NorthWest Biotherapeutics Inc (NWBO)

[Cheesey12]

Notes from presentation today:

1- I couldn't help but note that Matthias Preusser presented right before Dr. Liau. He was one of the physicians to write an article slamming the Phase 3 results presented in Jama. There was no interaction between he and Dr. Liau.
2. It was about 8-9 mins long. She moved very quickly. She basically gave an overview of the study criteria and discussed the issues with progression free survival. She specifically noted they changed the endpoints and developed the SAP prior to being unblinded. This was important to note as this seems to be unclear to naysayers including the aformentioned Preusser.
3. She seemed upbeat and proud of the results.
4. There was a "limitations" page to her presentation. She specifically noted this unfortunately was not a radomnly controlled trial (RCT) however...she noted "this does not mean the results are not valid. It just means this is a lower level of evidence than an RCT." She spoke on how she hopes this trial leads to more sponsers of trials to release patient level data from past trials so more external controls can be formulated and "less patients in trials need to undergo the standard of care."
5. Her last page was about combination therapies. I vaguely remember she lead off this slide.."and possibly most exciting " the potential for combinations therapies ....and went into DCVax-L getting T-cells going ect.

I hope this helps. Not comprehensive but...just shooting down some thoughts from memory.