Anavex Life Sciences Corp (AVXL)

[georgejjl]

Anavex's blarcamesine and/or Anavex 3-71 can treat and/or prevent ALS (Lou Gehrig's disease)

Sigma-1 receptor maintains ATAD3A as a monomer to inhibit mitochondrial fragmentation at the mitochondria-associated membrane in amyotrophic lateral sclerosis

both s1R and ATAD3A are critical factors of the MAM to maintain mitochondrial homeostasis, which are impaired in neurological diseases. Targeting s1R–ATAD3A axis at the MAM to prevent mitochondrial dysfunction would lead to development of a novel therapeutic strategy for neurodegenerative diseases.

https://www.sciencedirect.com/science/article/pii/S0969996123000451?via%3Dihub

Good luck and GOD bless,