In a situation like this selling too much too soon when the stock first moves up from being undervalued for a long time is usually the biggest mistake you will ever make. So that is still a very big concern for me.
OTOH what has the market done to me empirically over the last 2.5 years? Whether it's because of manipulators keeping a lid on the stock, or because market level forces like weak biotech sector as a whole keeping us sharply in check, $2 has been a repeated local high where 3 times you could have doubled or tripled whatever number of shares you had sold and bought back, while if you stubbornly held on refusing to sell a share you've bought a lot of frustration unless you've got massive amounts of patience.
I'm not going to risk selling 10-15% of my shares at $2 but I don't plan on sitting on my hands again watching the stock run to $2 and refusing to sell a single share. If you don't sell any you risk holding and watching yet another run up above $2 then back down below $1 while if you start selling at any arbitrary point e.g. $2 or $2.50 or $3 then of course you risk selling at $2 only to see it run to $5 without any big pullback. So maybe I'll be selling 3-5% for $2 next time it gets there. I'll have to wait and sell. Don't want to risk selling much 'very early' but I sure as hell don't want to sit through another run to $2 followed by an immediate sudden drop to $0.70 without selling any.
I don't have any hard-coded algorithm on, just gonna see what drives a price move if I can, and react with a wild ass guess or sell enough to close out 1-2 specific debts, for example. Anyway that's what I'm feeling like tonight.
