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Re: HappyLibrarian post# 557620

Sunday, 01/08/2023 10:26:22 AM

Sunday, January 08, 2023 10:26:22 AM

Post# of 698798
You don't get the point. I am talking about a competent person who can persuade major media outlets, even the FOX,which in your word with some truth though had been taken advantage of, to come onboard reporting the breakthrough results of Northwest Bio.

The person would present them the JAMA Oncology paper;

Would precisely explain how pseudo-progression changes the primary endpoint from PFS to OS, as a result it prolongs the trial duration;

Also because of the FDA's mandate for crossover, SAP must be revised and ECA would be used in comparison;

The trial results are indeed as JAMA Oncology reported positive with clinically meaningful and statistically significant results for nGBM, a significant improvement for 17 years, and for rGBM, an even more significant improvement for over 20 years; and

The implication of the positive trial results now for GBM is broad and huge for the vaccine can potentially be used to treat all solid tumors, and can be an essential part of cure for many cancers in combination.

After that I think the media would understand better Northwest Bio's stance, and I don't think even FOX would feel it would loss face if it follows up and reports the final results of the trial it reported before. And some of them may feel if not report now, it would miss out truly a breaking news with huge positive implication for years to come.
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