InvestorsHub Logo
Followers 91
Posts 11342
Boards Moderated 0
Alias Born 06/06/2014

Re: peeved post# 390669

Thursday, 12/08/2022 4:31:11 PM

Thursday, December 08, 2022 4:31:11 PM

Post# of 462121
Trevelyan is a pretty well known and intelligent biotech analyst, and has been quite skeptical of Cassava's research too:
https://ajtrev.substack.com/p/memory-games-part-i-the-data-is-available
He's pointing out things similar to Doc328's concerns: that we didn't use the most robust statistical tests (eg, one-sided t-test vs two-sided) making our p-val's literally less significant; and that we don't specify # of dropouts. He criticizes our use of SE instead of SD, but we're dealing with endpoint means of the individual scores not the scores themselves, so I don't see an issue there.

He smells a rat. To be fair to him, there are occasional shenanigans in biotechs' trial stats. It's one of the reasons you should know stats to be an investor in this sector, otherwise you can get misled. Biotech CEO's want to put the best spin reasonable on data. And their definition of "best spin reasonable" varies.

When you claim you "met all endpoints" on a very public TLR, but conspicuously under-report a primary endpoint, that's like bleeding in a pool of sharks. You better swim fast.
Volume:
Day Range:
Bid:
Ask:
Last Trade Time:
Total Trades:
  • 1D
  • 1M
  • 3M
  • 6M
  • 1Y
  • 5Y
Recent AVXL News