Anavex Life Sciences Corp (AVXL)

[VuBru]

Your point about needing increased statistical power of the full sample is a reasonable argument, but depends on whether there was increased efficacy with greater dose as was clear in past studies. You sound like you do research. I am sure you know that if there is a dose response effect, the 50mg group would show higher significance than was reported for the combined group and would be in effect pulling up the significance of the "laggards" in the 30mg group (which may not be significant). FWIW - My prediction is that 50mg showed efficacy on primary endpoints well under p<.025.