Anavex Life Sciences Corp (AVXL)

[ckent]

Exactly, Missling has always been very conservative and careful when speaking about efficacy, maybe not so much with timelines, but definitely very tempered when speaking of efficacy. During conferences before the P2a and OLE, he would hedge saying things like he was "cautiously optimistic." He has stopped doing this. He no longer uses hedge phrases nor needs to hedge since he's just stating facts based on previous trials.

He wants us to remember facts. "I want you to remember the numbers of the doses here for a reason... placebo declined... the medium dose stopped the decline... but the high dose group was above baseline... so patients coming into the trial came out with better cognitive features. And the reason I want you to remember these doses is that it's exactly the same doses as in the upcoming Alzheimer's study. Placebo, thirty, fifty." Facts!