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Re: Whalatane post# 392883

Monday, 11/07/2022 8:42:25 AM

Monday, November 07, 2022 8:42:25 AM

Post# of 423980
Kiwi - It is not that it takes 4 years for EPA to work. It is that it takes 4 years for enough events to occur that allow you to see that it works in this particular population. Higher risk populations will show more rapid benefits. RRR will likely be bigger at higher EPA doses and in non-Asian samples. The RESPECT results are mechanistically compelling to a scientist - the marginal significance of the primary outcome is irrelevant in terms of supporting REDUCE-IT findings. It is the effect size that matters and the clear link between EPA levels and CV benefits. Assuming Germany has scientists evaluating supporting literature as part of their decision making process, I would think this new study would help.
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