Saturday, October 22, 2022 1:29:55 PM
Also remember that older patients in the original treatment arm did not tolerate chemo/rad as well and probably had reduced rates and these older folks performed better than expected. For example, at 36 months those 65 plus and newly diagnosed receiving treatment were 550% more likely to be alive than historical comps. Four and five year survivors were compared at 6 of 50 and 5 of 50 to zero in historical comparators. Kind of a big deal and needing further explanation but Dr. Ashkan definitely pointed to reduced chemo/rad tolerance and use as a probable causal link. Best wishes.
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