Anavex Life Sciences Corp (AVXL)

[RedShoulder]

Reverse Rett negative comments about Acadia's drug Trofinetide:

The following points add to our reservations about this application:

There have been some anecdotal reports from families in America sharing positive experiences of the Trofinetide Lavender study. ?However, the data which have been shared by Acadia to date, only show very small differences between patients treated with Trofinetide over patients who received placebo. Also, a relatively high number of people (20%) left the trial; the most commonly cited side effect was diarrhoea. More evidence is needed before the community can arrive at a conclusion regarding Trofinetide and its potential for improving symptoms in people with Rett Syndrome.?

https://www.reverserett.org.uk/this-weeks-trofinetide-announcement/

Once Anavex's A2-73 is approved, virtually all Rett patients will be on Anavex's A2-73 which has much better efficacy, without the adverse side effects that Acadia's Trofinetide.