Revance Therapeutics Inc (RVNC)

[mouton29]

Mostly favorable but the plastic surgeon and Fox news interviewer claim that that some people will avoid Daxxi because the longer lasting effect means that side effects last longer, e.g., drooping eyelid (ptosis) for six months. This misses: (i) Daxxi rate of ptosis is much lower than the Botox rate of ptosis (about 1% for Daxi aggregating all patients in the trial, open and randomized, compared to 3% for Botox) and (ii) ptosis resolves more quickly than the median treatment effect, 58 days according to the report in the Journal of the American Academy of Dermatology.

https://www.jaad.org/article/S0190-9622(19)32459-4/fulltext (see the last footnote to table 1)