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Re: HyGro post# 506527

Friday, 08/19/2022 8:00:40 PM

Friday, August 19, 2022 8:00:40 PM

Post# of 721734
The original endpoints were confounded. The original OS endpoint compared to in-trial placebo, and was confounded due to crossover.

The NEW endpoints, changed before datalock, are NOT confounded. The new OS endpoint compares to an ECA, which crossover does not confound.

There are concerns with NWBio, but this is not one of them. There’s nothing else to say—if you don’t understand this by now then maybe you won’t ever and that’s fine, don’t invest.
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